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NIDCR News 2023

An illustration depicting dry mouth,
December 18, 2023
Turning the Tap Back On

From gene therapy to salivary gland regeneration, NIDCR-supported scientists aim to restore saliva flow for people with diseased or damaged glands.

Research Brief
A photo of the physician chatting with her staff while treating a patient.
November 21, 2023
NIDCR is PRIMED to move AHEAD with IMPACT: Institute Awards $14 Million to Tackle Unsolved Clinical Challenges

NIDCR issued 26 awards, totaling $14.1 million, as part of three bold new initiatives to tackle unsolved clinical challenges related to head and neck cancer, temporomandibular disorders, and practice-based dental research.

Announcement
TMDs can affect either of the jaw joints and can become lasting chronic pain conditions.
November 15, 2023
Looking Forward to Greater IMPACT on Temporomandibular Disorders

Decades of NIDCR research has expanded understanding of temporomandibular disorders and orofacial pain in general.

Research Brief
Two children are standing side by side and smiling at the camera.
November 14, 2023
A 25-Year Scientific Quest Offers Hope for Patients With Rare Disorder

Patients and scientists celebrated the 25-year legacy of NIDCR research on fibrous dysplasia/McCune-Albright syndrome and shared their hopes for the future.

Research Brief
Photo of a baby laying on his back.
November 14, 2023
Earlier May Be Better for Isolated Cleft Palate Surgery

An international clinical trial suggests that early surgery for isolated cleft palate is more likely to benefit a child's speech.

Research Brief
Nobel prize
October 16, 2023
NIDCR Funded Winner of 2023 Nobel Prize in Physiology or Medicine

NIDCR congratulates former institute grantee Dr. Drew Weissman for being a co-recipient of the 2023 Nobel Prize in Physiology or Medicine. 

Announcement
Photo of NIDCR Senior Research Physician, Rachel I. Gafni, M.D., examines a clinical trial participant with ADH1
October 13, 2023
Investigational Drug Restores Parathyroid Function in Rare Disease

An experimental drug, encaleret, showed promise for treating autosomal dominant hypocalcemia type 1 in an NIDCR-led trial. The rare genetic disorder, marked by low blood calcium levels, can cause symptoms from muscle cramps to life-threatening seizures.

Press Release
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October 3, 2023
Three Germ Layers and a Paradigm Shift

NIDCR researchers made an unexpected discovery that helps to answer a long-standing mystery tied to a group of stem cells that are key to vertebrate development.

Research Brief
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September 6, 2023
A Quarter-Century Quest to Treat a Rare Disease
For 25 years, NIDCR scientists have been looking for better ways to treat fibrous dysplasia/McCune-Albright syndrome, a rare disorder of the bones, skin, and endocrine system.
Research Brief
An artistic depiction of a scientist working working in a lab.
August 9, 2023
Legacies of the Pandemic
The COVID-19 pandemic thrust NIDCR science into the spotlight. Research on virus biology, detection methods, and more could ready us for future pandemics.
Research Brief
NIH leaders, members of the scientific community, and federal and scientific society partners gathered for a symposium to kick off NIDCR’s 75th anniversary.
July 14, 2023
NIH Leaders, Scientific Community, Federal Partners Celebrate the Past, Chart the Future

NIDCR held a symposium on June 27, 2023, to kick off its year-long 75th anniversary celebration.

Research Brief
An abstract image showing human faces.
July 13, 2023
Cracking the Code to the Human Face

What shapes our faces? Decades’ worth of NIDCR research is enabling scientists to crack the code of facial appearance and craniofacial conditions.

Research Brief
Skeletal stem cells from healthy mice formed clusters of cartilage-producing cells, above, that were later replaced by bone.
May 8, 2023
Building Back Broken Bones
NIDCR scientists found that mice lacking a protein called biglycan developed weak bones that healed poorly from fractures. The findings could inform strategies to better repair fractures and treat disorders marked by bone loss, such as osteoporosis.
Research Brief
NIDCR Director Dr. D'Souza moderated a panel of intramural scientists.
April 12, 2023
Intramural Investigators Take the Stage at Scientific Strides Anniversary Symposium in Oregon

NIDCR began its slate of 75th anniversary events on March 17, 2023, with a symposium called “Scientific Strides of the NIDCR: 75 Years and Beyond.”

Research Brief
Bone scans of a patient before (left) and after (right) a six-month denosumab treatment show reduced turnover within fibrous dysplasia lesions (dark-colored patches).
April 4, 2023
Therapy for Rare Bone Disorder Shows Promise in NIH Clinical Trial
An NIDCR-led clinical trial showed promise for treating fibrous dysplasia, a rare skeletal disorder. The medication, denosumab, is the first to reduce the bone-weakening process in the disorder.
Press Release
A stock image showing a dentist's office.
March 23, 2023
How Data Science and Digital Dentistry Can Improve Dental Care
Advances in digital technologies and data science hold promise for improving oral health care and enabling personalized treatment.
Research Brief
An artistic depiction of people standing next to each other while looking to the left.
March 23, 2023
Report Reveals Striking Differences in Oral Health Care Across the U.S.
Scientific advances have not been fully translated into accessible oral health care for communities in need. Improving access to safe, affordable, and holistic medical and dental care can mitigate inequities.
Research Brief

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